Obtención de andamios de colágeno de crestas de pollo y piel de cerdo para la reparación del sistema cardiovascular

Authors

  • Janet Carvajal de la Osa Universidad Tecnológica de la Habana. “José Antonio Echeverría”, Cujae
  • Amanda Pacheco Leal Centro de Estudios Avanzados de Cuba (CEAC)
  • Yaimara Nuevo Artíles Centro Nacional de Electromedicina (CNE)
  • Carlos Rafael Figueroa Hernández Universidad Tecnológica de la Habana. “José Antonio Echeverría”, Cujae
  • Reyniel Gómez González Universidad Tecnológica de la Habana. “José Antonio Echeverría”, Cujae
  • Javier Luis Villegas Santos Universidad Tecnológica de la Habana. “José Antonio Echeverría”, Cujae
  • Yunier Serrano Riverio Centro Nacional de Investigaciones Científicas (CNIC)
  • Ahmed Valdés Martínez Centro de Estudios Avanzados de Cuba (CEAC)
  • Tania Rodríguez Moliner Universidad Tecnológica de la Habana. “José Antonio Echeverría”, Cujae
  • Juan Prohías Martínez Cardiocentro Hospital Hermanos Ameijeiras
  • Yenisel Díaz Roller Universidad Tecnológica de la Habana. “José Antonio Echeverría”, Cujae

Abstract

In the present work, collagen scaffolds were obtained by the lyophilization method, using chicken ridges and pig skin as source of origin. This process was carried out in molds to obtain the required shape and dimensions of the scaffolds. The characterizations were carried out using the SDS page acrylamide gel electrophoresis techniques and Fourier transform infrared spectrometry (FTIR), checking the presence of type I collagen in all cases. In addition, a stereoscopic analysis was made where it was observed that the scaffolds have a fibrous surface morphology packed in a compact way and with random orientation and interconnected pores. The characterizations showed that both the collagen and the scaffolds comply with the composition and morphology required to be used as a biomaterial in tissue regeneration.

Published

2021-06-21

How to Cite

Carvajal de la Osa, J. ., Pacheco Leal, A. ., Nuevo Artíles, Y. ., Figueroa Hernández, C. R. ., Gómez González, R. ., Villegas Santos, J. L. ., … Díaz Roller, Y. . (2021). Obtención de andamios de colágeno de crestas de pollo y piel de cerdo para la reparación del sistema cardiovascular. Revista Cubana De Ingeniería, 12(2), e279. Retrieved from https://rci.cujae.edu.cu/index.php/rci/article/view/778

Issue

Section

Original Articles